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| Pharmacogenetic testing is recommended on the FDA Drug label The USFDA-approved drug label for fluorouracil states that the drug is contraindicated in patients with known DPD deficiency. CPIC Dosing Guidelines for fluoropyrimidines recommends an alternative drug for patients who are homozygous for DPYD non-functional variants as these patients are typically DPD deficient and a 50% reduction for heterozygous patients. Being part of the programme. Please email us at vinods@igib.in What variants are presently being tested ? Pharmacogenetic testing in research mode for 5FU is available through GOMED for variants rs67376798 , rs3918290, rs5586062 and rs2297595 in DPD gene. Information Brochure | Genomic test request Please write a referral on your letterhead regarding the referral and the test you would be requesting. Pack the documents with the box you would be sending across Consent forms (one each for each patient) The consent forms for genomic analysis needs to be signed individually by each member (or parent/guardian in case the person is a minor). Each consent needs to be counter-signed by the investigator.
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